Gut microbiome screens could identify risk of Parkinson’s disease years before symptoms appear

Nature Medicine, Published online: 28 May 2026; doi:10.1038/s41591-026-04458-8

Innovative microbiome analysis revealed a part of the gut microbiome that changes coherently from healthy individuals across those with genetic risk of Parkinson’s disease to patients who are symptomatic. A large range of microbiome alterations within each of the three groups enables identification of individuals at greater risk of developing Parkinson’s disease. A healthy diet was inversely associated with these alterations and might mitigate disease risk.

Source: www.nature.com

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