Targeted removal of soluble Fms-like tyrosine kinase 1 in very preterm preeclampsia: a pilot trial

Nature Medicine, Published online: 27 April 2026; doi:10.1038/s41591-026-04333-6

Selective removal of the placental protein sFlt-1 via antibody-based apheresis was safe and was associated with modest reductions in blood pressure and prolongation of pregnancy in women with very preterm preeclampsia. The treatment supports conducting controlled trials to evaluate its safety and efficacy at a larger scale.

Source: www.nature.com